1244 - PRECISE Trial Response and Consequences of Stress in Persons with Different Disability Types

The CAL-STAR study enrolled 853 Californians to study how perceived stress (measured by the perceived stress scale (PSS-10) influences multisystem biobehavioral functioning. A subset with high PSS (n=426)  participated in a randomized controlled trial evaluating the efficacy of PRECISE to reduce perceived stress. The consequences of stress scale measured which biobehavioral domains were most affected by stress (thinking style, social relationships, sleep, eating, and physical activity). We used the Behavioral Risk Factor Surveillance System disability questions (6 questions related to difficulty seeing, hearing, walking/climbing stairs, dressing/bathing, and doing errands), combined into 4 disability categories using hierarchical clustering (mobility, cognitive, sensory, none). 

Results: In comparison to the none group, PSS scores were highest in the mobility group (b=6.20, p< 0.001), followed by the cognitive (b=3.10, p< 0.001) and sensory groups (b=1.89, p=0.023).  Compared to the none group, CSS domain scores in the mobility group did not significantly differ in the domains of physical activity, eating, or sleep, but were higher in the social relationships (b=0.90, p=0.045) and thinking style domains (b=1.17, p=0.011). In contrast, the sensory group did not significantly differ from the none group in the social and thinking style domains (p>0.05) but was higher in the other three domains. The cognitive  group had higher CSS scores than the none group in all domains, with sleep being the highest (b=1.80, p< 0.001), followed by thinking style (b=1.53, p< 0.001).  Disability type did not affect treatment response to PRECISE.

Conclusions: Although people with different disability types differed in their levels of stress and related consequences,  disability type did not affect treatment response to  PRECISE, suggesting that the intervention is beneficial regardless of disability type.