914 - Recurrent Inflammatory Myositis: A Case of Rapid Relapse

Idiopathic inflammatory myopathy (IIM) entails four subtypes: dermatomyositis, polymyositis, immune-mediated necrotizing myopathy, and inclusion body myositis. Patients typically present with significant proximal muscle weakness, elevated muscle enzymes, and increased inflammatory markers including ESR and CRP. Diagnostic confirmation can be supported by EMG findings, muscle biopsy abnormalities and serological testing. In this case, statin-induced myopathy was initially considered however, this was deemed less likely given the recurrence of symptoms despite discontinuation of atorvastatin and the absence of HMGCR autoantibodies. This case underscores the importance of recognizing early recurrence of IIM in order to initiate treatment early and minimize functional decline. Timely intervention in this case enabled the patient to preserve modified independence in activities of daily living and maintain functional ambulation.

Conclusions: This case illustrates the relapsing course of idiopathic inflammatory myopathy. Even after initial improvement with immunosuppressive therapy, patients may experience recurrence, leading to renewed muscle weakness and functional decline. Continuous monitoring and early recognition of disease activity are essential to guide timely intervention. Prompt escalation of therapy, including corticosteroids and IVIG, can significantly improve outcomes and preserve mobility. This case reinforces the importance of proactive management to optimize recovery and maintain quality of life for patients with IIM