Associate Scientist at HSS and Assistant Professor at WCMC
Hospital for Special Surgery
Dr. Miguel Otero is an Associate Scientist in the Orthopedic Soft Tissue Research Program, Associate Director of Translational Research of the HSS Center for Regenerative Medicine, Co-Director of the Derfner Foundation Precision Medicine Laboratory, and Director of the Molecular Histopathology Core Laboratory at the Hospital for Special Surgery (HSS), and Assistant Professor of Cell and Developmental Biology in Orthopaedic Surgery at Weill Cornell Medical College (WCMC).
Dr. Otero aims to deepen our understanding of the altered signaling pathways that prompt joint tissue disruption in osteoarthritis (OA), with emphasis in developing precision-medicine based approaches to improve patient care. Working in multidisciplinary teams with HSS surgeons, rheumatologists, engineers, pathologists, bioinformaticians, and radiologists, Dr. Otero uses comprehensive state-of-the-art approaches to analyze patient samples and define knee OA patient subtypes, assess how different joint tissues contribute to OA disease, and test non-surgical therapies in clinical trials. His laboratory integrates multimodal analyses of clinical samples with model organism and cell culture assays to understand disease mechanisms and uncover potential therapeutic targets.
Saturday, February 21, 2026
1:30 PM - 2:30 PM AST
